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[ Pobierz całość w formacie PDF ]//-->WORLD HEALTH ORGANIZATIONINTERNATIONAL AGENCY FOR RESEARCH ON CANCERIARC Monographs on the Evaluationof Carcinogenic Risks to HumansVOLUME 88Formaldehyde, 2-Butoxyethanoland 1-tert-Butoxypropan-2-olThis publication represents the views and expert opinionsof an IARC Working Group on theEvaluation of Carcinogenic Risks to Humans,which met in Lyon,2–9 June 20042006IARC MONOGRAPHSIn 1969, the International Agency for Research on Cancer (IARC) initiated a programme on the evaluation ofthe carcinogenic risk of chemicals to humans involving the production of critically evaluated monographs onindividual chemicals. The programme was subsequently expanded to include evaluations of carcinogenic risks asso-ciated with exposures to complex mixtures, life-style factors and biological and physical agents, as well as those inspecific occupations.The objective of the programme is to elaborate and publish in the form of monographs critical reviews of dataon carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations; toevaluate these data in terms of human risk with the help of international working groups of experts in chemicalcarcinogenesis and related fields; and to indicate where additional research efforts are needed.iarc.fr/This programme has been supported by Cooperative Agreement 5 UO1 CA33193 awarded since 1982 by theUnited States National Cancer Institute, Department of Health and Human Services. Additional support has beenprovided since 1986 by the European Commission, Directorate-General EMPL (Employment, and Social Affairs),Health, Safety and Hygiene at Work Unit, and since 1992 by the United States National Institute of EnvironmentalHealth Sciences.This publication was made possible, in part, by a Cooperative Agreement between the United States Environ-mental Protection Agency, Office of Research and Development (USEPA-ORD) and the International Agency forResearch on Cancer (IARC) and does not necessarily express the views of USEPA-ORD.Published by the International Agency for Research on Cancer,150 cours Albert Thomas, 69372 Lyon Cedex 08, France©International Agency for Research on Cancer, 2006Distributed by WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland(tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int).Publications of the World Health Organization enjoy copyright protection in accordance with the provisionsof Protocol 2 of the Universal Copyright Convention. All rights reserved.The International Agency for Research on Cancer welcomes requests for permission to reproduce or translate itspublications, in part or in full. Requests for permission to reproduce or translate IARC publications−whether for saleor for noncommercial distribution−should be addressed to WHO Press, at the above address (fax: +41 22 791 4806;email: permissions@who.int).The designations employed and the presentation of the material in this publication do not imply the expressionof any opinion whatsoever on the part of the Secretariat of the World Health Organization concerning the legal statusof any country, territory, city, or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsedor recommended by the World Health Organization in preference to others of a similar nature that are not mentioned.Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.The IARC Monographs Working Group alone is responsible for the views expressed in this publication.IARC Library Cataloguing in Publication DataFormaldehyde, 2-Butoxyethanol and 1-tert-Butoxypropan-2-ol/IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2004 : Lyon, France)(IARC monographs on the evaluation of carcinogenic risks to humans ; v. 88)1. Carcinogens, Environmental−toxicity 2. Ethylene Glycols−toxicity3. Formaldehyde−toxicity 4. Propylene Glycols−toxicityI. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans II. SeriesISBN 92 832 1288 6ISSN 1017-1606(NLM Classification: W1)PRINTED IN FRANCE1234512345Formaldehyde and 2-butoxyethanol are intermediates used in the chemicalindustry.Formaldehyde-based resins are used in the manufacture of plywood, particle-board, furniture, cabinets and other composite wood products.The general population can be exposed to 2-butoxyethanol and 1-tert-butoxy-propan-2-ol by inhalation or skin contact with cleaning products containingthese glycol ethers.Embalmers, pathologists and anatomists are exposed to formaldehyde, apreservative and embalming agent.Formaldehyde is also present as an antimicrobial agent in many cosmeticproducts.Cover design: Georges Mollon, IARC [ Pobierz całość w formacie PDF ]
