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[ Pobierz całość w formacie PDF ]S T U D E N T C O M PA N I O N
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Biochemistry
LIFE AT
THE MOLECULAR
LEVEL
Voet Voet Pratt
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Akif Uzman Jerry Johnson Joseph Eichberg William Widger
Donald Voet Judith G. Voet Charlotte W. Pratt
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STUDENT COMPANION TO ACCOMPANY
FUNDAMENTALS OF
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Fourth Edition
Akif Uzman
University of Houston
Jerry Johnson
University of Houston
Joseph Eichberg
University of Houston
William Widger
University of Houston
Donald Voet
University of Pennsylvania
Judith G. Voet
Swarthmore College
Charlotte W. Pratt
Seattle, Washington
JOHN WILEY & SONS, INC
Cover Designer Madelyn Lesure
Cover Illustration Norm Christiansen
Cover Photos
(Vitruvian Man): © Odysseus/Alamy and © Dennis Hallinan/Alamy
Molecular structures clockwise from top: based on X-ray structures that were respectively determined
by Richard Dickerson and Horace Drew, Caltech; Gerard Bunick, University of Tennessee; Thomas
Steitz, Yale University; Alfonso Mondragón, Northwestern University; Venki Ramakrishnan, MRC
Laboratory of Molecular Biology, Cambridge, U.K.; Andrew Leslie and John Walker, MRC Laboratory
of Molecular Biology, Cambridge, U.K.
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Copyright © 2012
John Wiley & Sons, Inc.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or
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Student Companion (paperback)
ISBN-13 978-1-1182-1827-3
Printed in the United States of America
10 9 8 7 6 5 4 3 2 1
Contents
1
Introduction to the Chemistry of Life
1
2
Water
9
3
Nucleotides, Nucleic Acids, and Genetic Information
21
4
Amino Acids
29
5
Proteins: Primary Structure
40
6
Proteins: Three-Dimensional Structure
49
7
Protein Function: Myoglobin and Hemoglobin, Muscle
Contraction, and Antibodies
60
8
Carbohydrates
72
9
Lipids and Biological Membranes
80
10
Membrane Transport
90
11
Enzymatic Catalysis
96
12
Enzyme Kinetics, Inhibition, and Control
108
13
Biochemical Signaling
121
14
Introduction to Metabolism
128
15
Glucose Catabolism
137
16
Glycogen Metabolism and Gluconeogenesis
146
17
Citric Acid Cycle
154
18
Electron Transport and Oxidative Phosphorylation
160
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